Artvigil: Enhance Wakefulness and Cognitive Performance
Artvigil
| Product dosage: 150 mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 30 | $2.17 | $65.00 (0%) | 🛒 Add to cart |
| 60 | $1.40 | $130.00 $84.00 (35%) | 🛒 Add to cart |
| 100 | $1.18 | $216.67 $118.00 (46%) | 🛒 Add to cart |
| 200 | $1.02 | $433.33 $204.00 (53%) | 🛒 Add to cart |
| 300 | $0.91 | $650.00 $274.00 (58%) | 🛒 Add to cart |
| 500 | $0.80
Best per pill | $1083.33 $398.00 (63%) | 🛒 Add to cart |
Synonyms | |||
Artvigil is a prescription medication containing armodafinil, the R-enantiomer of modafinil, designed to promote wakefulness in individuals experiencing excessive sleepiness due to narcolepsy, obstructive sleep apnea, or shift work sleep disorder. As a eugeroic agent, it functions by altering the natural chemicals (neurotransmitters) in the brain that regulate the sleep-wake cycle, thereby improving alertness without the jitteriness or euphoria associated with traditional stimulants. Its extended half-life and selective mechanism of action make it a preferred choice among healthcare providers for managing daytime sleepiness while minimizing potential for abuse.
Features
- Active ingredient: Armodafinil (150 mg per tablet)
- Pharmacological class: Eugeroic (wakefulness-promoting agent)
- Form: Oral tablet
- Half-life: Approximately 15 hours
- Bioavailability: High, with peak plasma concentration reached in about 2 hours
- Excretion: Primarily renal, with some fecal elimination
Benefits
- Promotes sustained wakefulness and reduces excessive daytime sleepiness
- Enhances cognitive functions such as memory, focus, and executive function
- Improves quality of life for individuals with sleep disorders by supporting normal daily activities
- Lower abuse potential compared to amphetamine-based stimulants
- Allows for improved occupational performance, especially in shift workers
- May aid in the management of fatigue associated with certain medical conditions
Common use
Artvigil is commonly prescribed for the treatment of excessive sleepiness associated with narcolepsy, obstructive sleep apnea (OSA) (as adjunctive therapy to standard treatment for residual sleepiness), and shift work sleep disorder (SWSD). It is also used off-label in some cases to address fatigue in conditions such as multiple sclerosis, depression, and Parkinson’s disease, though such uses should be carefully evaluated by a healthcare professional.
Dosage and direction
The recommended dosage of Artvigil is 150 mg or 250 mg taken orally once daily, in the morning for narcolepsy or OSA, or approximately one hour prior to the start of a work shift for SWSD. It should be taken with or without food, though a high-fat meal may delay absorption. Dosage adjustments may be necessary for patients with severe hepatic impairment. Do not crush or split tablets.
Precautions
Patients should be cautious when operating machinery or driving until they know how Artvigil affects them, as it may cause dizziness or impaired judgment. It is not recommended for use in patients with a history of left ventricular hypertrophy or ischemic ECG changes, chest pain, arrhythmia, or other significant cardiac symptoms. Use with caution in those with a history of psychosis, depression, or mania. Artvigil may interact with hormonal contraceptives; alternative or additional methods of contraception should be used during and for one month after treatment.
Contraindications
Artvigil is contraindicated in patients with known hypersensitivity to armodafinil, modafinil, or any component of the formulation. It should not be used in individuals with a history of symptomatic cardiovascular disease, including mitral valve prolapse syndrome, and those with a history of drug abuse.
Possible side effects
Common side effects may include headache, nausea, dizziness, insomnia, anxiety, and dry mouth. Less frequently, patients may experience palpitations, increased blood pressure, diarrhea, or nervousness. Serious but rare side effects include Stevens-Johnson syndrome, angioedema, multiorgan hypersensitivity reactions, and psychiatric symptoms such as aggression or hallucinations. Patients should seek medical attention if any severe reactions occur.
Drug interaction
Artvigil may interact with drugs that are substrates, inducers, or inhibitors of CYP3A4/5 enzymes. It can reduce the effectiveness of cyclosporine, hormonal contraceptives, and certain antifungals or antibiotics. Concurrent use with monoamine oxidase inhibitors (MAOIs) is not recommended. It may also potentiate the effects of drugs such as diazepam, phenytoin, or warfarin. Always inform your healthcare provider of all medications, including over-the-counter drugs and supplements.
Missed dose
If a dose is missed, take it as soon as possible unless it is close to the time of the next scheduled dose. Do not double the dose to make up for a missed one. Taking Artvigil late in the day may cause difficulty sleeping at night.
Overdose
Symptoms of overdose may include insomnia, central nervous system excitation, agitation, confusion, nausea, and tachycardia. In case of suspected overdose, seek immediate medical attention or contact a poison control center. Treatment is symptomatic and supportive; there is no specific antidote.
Storage
Store Artvigil at room temperature (20–25°C or 68–77°F), in a tightly closed container, away from light, moisture, and heat. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.
Disclaimer
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or medication. Do not disregard professional medical advice or delay in seeking it because of something you have read here.
Reviews
Clinical studies and patient reports generally indicate that Artvigil is effective in promoting wakefulness and improving cognitive function in indicated conditions. Many users report significant improvements in daytime alertness and productivity. However, individual responses may vary, and some users experience side effects such as headaches or sleep disturbances. Always follow your healthcare provider’s guidance for safe and effective use.