Astelin Nasal Spray: Fast-Acting Relief for Allergic Rhinitis Symptoms
Astelin
| Product dosage: 10ml | |||
|---|---|---|---|
| Package (num) | Per sprayer | Price | Buy |
| 2 | $23.00 | $46.00 (0%) | 🛒 Add to cart |
| 3 | $21.67 | $69.00 $65.00 (6%) | 🛒 Add to cart |
| 4 | $20.75 | $92.00 $83.00 (10%) | 🛒 Add to cart |
| 5 | $20.20 | $115.00 $101.00 (12%) | 🛒 Add to cart |
| 6 | $20.00 | $138.00 $120.00 (13%) | 🛒 Add to cart |
| 7 | $19.71 | $161.00 $138.00 (14%) | 🛒 Add to cart |
| 8 | $19.50 | $184.00 $156.00 (15%) | 🛒 Add to cart |
| 9 | $19.44 | $207.00 $175.00 (15%) | 🛒 Add to cart |
| 10 | $19.30
Best per sprayer | $230.00 $193.00 (16%) | 🛒 Add to cart |
Synonyms
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Astelin (azelastine hydrochloride) is a prescription antihistamine nasal spray clinically proven to provide rapid relief from seasonal and perennial allergic rhinitis symptoms. As a second-generation antihistamine with both H1-receptor blocking and anti-inflammatory properties, Astelin offers a targeted approach to managing nasal allergy symptoms directly at the source. Its unique mechanism of action provides comprehensive symptom control without the systemic sedative effects commonly associated with oral antihistamines, making it an optimal choice for patients seeking effective allergy management while maintaining daytime alertness and productivity.
Features
- Contains azelastine hydrochloride 137 mcg per spray
- H1-receptor antagonist with additional anti-inflammatory properties
- Rapid onset of action with symptom relief within 15-30 minutes
- Twice-daily dosing regimen for consistent 24-hour coverage
- Alcohol-free formulation with minimal systemic absorption
- Metered-dose pump delivery system for precise medication administration
- Preservative-free formulation in most markets
- Compatible with other allergy medications when medically supervised
Benefits
- Provides rapid relief from sneezing, nasal itching, runny nose, and nasal congestion
- Reduces inflammatory mediators in the nasal passages for comprehensive symptom control
- Minimizes systemic side effects through localized nasal delivery
- Maintains cognitive function without causing significant drowsiness
- Offers convenient twice-daily dosing for consistent symptom management
- Improves quality of life by enabling normal daily activities during allergy season
Common use
Astelin Nasal Spray is primarily indicated for the treatment of symptoms associated with seasonal allergic rhinitis (hay fever) and perennial allergic rhinitis in adults and children 5 years of age and older. Seasonal allergic rhinitis typically occurs in response to outdoor allergens such as tree, grass, and weed pollens, while perennial allergic rhinitis occurs year-round due to indoor allergens including dust mites, pet dander, and mold spores. Healthcare providers may also prescribe Astelin off-label for vasomotor rhinitis and as adjunctive therapy for nasal polyps, though these uses require medical supervision and are not FDA-approved indications.
Dosage and direction
For adults and children 12 years of age and older: The recommended dosage is 1 or 2 sprays per nostril twice daily. For children 5 to 11 years of age: The recommended dosage is 1 spray per nostril twice daily. Prior to initial use, the pump must be primed by releasing 4 sprays into the air away from the face until a fine mist appears. If the product has not been used for 3 or more days, reprime with 2 sprays. Shake the bottle gently before each use. Blow nose gently to clear nasal passages before administration. Tilt head slightly forward and insert tip into nostril, pointing away from the nasal septum. Close the opposite nostril with finger and inhale gently while spraying. Repeat in other nostril. Avoid blowing nose for 15 minutes after administration.
Precautions
Patients should inform their healthcare provider if they experience nasal septal perforations, ulcerations, or recurrent epistaxis (nosebleeds). Use caution when operating machinery or engaging in activities requiring alertness until response to the medication is known, as somnolence has been reported in some patients. The bottle should not be inserted into the nostril at an upward angle to avoid directing the spray toward the nasal septum. Patients with recent nasal surgery, nasal trauma, or nasal ulcers should consult their physician before use. The product may cause temporary alterations in taste sensation; this effect typically diminishes with continued use. Patients should avoid allowing the spray to contact the eyes.
Contraindications
Astelin is contraindicated in patients with known hypersensitivity to azelastine hydrochloride or any component of the formulation. The product should not be used by patients who have experienced previous allergic reactions to other antihistamine medications. Contraindications include patients with severe renal impairment requiring dialysis, as safety and efficacy have not been established in this population. The nasal spray formulation is not intended for ophthalmic use and is contraindicated for administration in the eyes.
Possible side effects
Common side effects (occurring in >2% of patients) include bitter taste (19.7%), somnolence (11.5%), nasal burning (4.1%), pharyngitis (3.4%), dry mouth (3.0%), and headache (2.8%). Less common side effects (<2%) include dizziness, epistaxis, weight increase, nasal ulceration, sneezing, and rhinitis. Rare but serious adverse reactions may include anaphylaxis, bronchospasm, and nasal septal perforation. Patients should discontinue use and seek immediate medical attention if they experience difficulty breathing, swelling of the face or throat, or severe nasal irritation or bleeding.
Drug interaction
Concomitant use with CNS depressants including alcohol, sedatives, and tranquilizers may enhance sedative effects. Azelastine may potentiate the effects of other anticholinergic drugs. No clinically significant interactions have been observed with pseudoephedrine, cimetidine, or theophylline. However, patients should inform their healthcare provider of all medications, including prescription drugs, over-the-counter medications, and herbal supplements, before starting Astelin therapy. Caution is advised when using with other nasally administered medications due to potential for increased local irritation.
Missed dose
If a dose is missed, it should be taken as soon as remembered unless it is almost time for the next scheduled dose. In that case, skip the missed dose and resume the regular dosing schedule. Do not double the dose to make up for a missed administration. Maintaining consistent twice-daily dosing provides optimal symptom control, but occasional missed doses are unlikely to significantly impact overall efficacy. Patients should establish a routine (such as morning and evening administration) to improve adherence.
Overdose
In case of accidental overdose, symptomatic and supportive treatment should be instituted. Symptoms of overdose may include somnolence, dizziness, nausea, vomiting, and abdominal discomfort. There is no specific antidote for azelastine hydrochloride overdose. Given the medication’s limited systemic absorption when administered nasally, systemic effects are unlikely unless large volumes are ingested orally. In cases of intentional or accidental ingestion, activated charcoal may be considered if administered within one hour of ingestion. Patients experiencing overdose symptoms should seek immediate medical attention or contact a poison control center.
Storage
Store Astelin Nasal Spray at controlled room temperature between 20°C to 25°C (68°F to 77°F). Do not freeze. Keep the bottle tightly closed and stored in an upright position. Protect from light and excessive heat. Discard the product 30 days after opening, even if medication remains. Keep out of reach of children and pets. Do not transfer the medication to another container. The product should be visually inspected for discoloration or particulate matter before each use; discard if abnormalities are observed.
Disclaimer
This information is provided for educational purposes only and does not constitute medical advice. Astelin is a prescription medication that should be used only under the supervision of a qualified healthcare professional. Individual results may vary, and not all patients will experience the same benefits or side effects. Patients should consult their healthcare provider for proper diagnosis and treatment recommendations based on their specific medical condition, allergy profile, and overall health status. Never disregard professional medical advice or delay seeking treatment based on information contained in this document.
Reviews
Clinical studies demonstrate that Astelin provides significant improvement in total nasal symptom scores compared to placebo, with 65% of patients reporting meaningful symptom relief within the first hour of administration. Patient satisfaction surveys indicate high rates of continued use due to effective symptom control and minimal systemic side effects. Healthcare providers frequently report positive outcomes when using Astelin as monotherapy or in combination with other allergy medications for patients with moderate to severe allergic rhinitis. Real-world evidence supports the sustained efficacy and safety profile observed in clinical trials, with particular appreciation for the rapid onset of action and lack of significant sedation.