Bactroban Ointment 5g: Topical Antibiotic for Skin Infection Resolution

Bactroban Ointment 5g

Bactroban Ointment 5g

Bactroban Ointment (mupirocin ointment) is a topical (for the skin) antibiotic used to treat infections of the skin such as impetigo.
Product dosage: 20mg
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Synonyms

Bactroban Ointment 5g is a prescription topical antibiotic containing mupirocin 2% w/w, specifically formulated for the treatment of bacterial skin infections. It is indicated for primary infections like impetigo and secondary infected traumatic skin lesions. Its targeted mechanism of action inhibits bacterial protein synthesis, making it a first-line choice for infections caused by Staphylococcus aureus and Streptococcus pyogenes. This formulation is designed for localized application, minimizing systemic absorption and associated risks.

Features

  • Contains mupirocin 2% w/w as the active pharmaceutical ingredient
  • Available in a 5g tube for precise, convenient dosing
  • White, translucent, water-soluble ointment base
  • Bactericidal activity against Gram-positive bacteria
  • Minimal systemic absorption when applied topically as directed
  • Prescription-only medication requiring professional diagnosis

Benefits

  • Effectively eradicates common skin pathogens, reducing infection duration and severity
  • Promotes faster healing of infected skin lesions, minimizing scarring risk
  • Targeted topical application reduces risk of systemic side effects compared to oral antibiotics
  • Prevents spread of infection to other body areas or to other individuals
  • Convenient dosing regimen supports treatment adherence
  • Helps prevent complications from untreated bacterial skin infections

Common use

Bactroban Ointment is primarily prescribed for the treatment of impetigo, a contagious bacterial skin infection characterized by honey-colored crusted lesions. It is also indicated for secondary infected traumatic skin lesions, including small lacerations, abrasions, and sutured wounds that have become infected. Healthcare providers may also consider its use for other localized skin infections caused by susceptible organisms, particularly in cases where methicillin-resistant Staphylococcus aureus (MRSA) is suspected or confirmed, though susceptibility testing is recommended.

Dosage and direction

Apply a small amount of ointment to the affected area three times daily. The area may be covered with a gauze dressing if desired. Wash hands before and after application unless hands are the treated area. The typical treatment duration is 7-10 days, though your physician may adjust this based on clinical response. If no improvement is seen within 3-5 days, re-evaluation by a healthcare provider is recommended. Do not use for longer than prescribed unless directed by your physician.

Precautions

Use only as directed by a healthcare professional. Avoid contact with eyes, nose, mouth, and other mucous membranes. Do not apply to large body areas or use under occlusive dressings unless specifically instructed by a physician. Discontinue use and consult your doctor if excessive irritation, rash, or allergic reaction occurs. Not for ophthalmic, intranasal, or intravaginal use. Use with caution in patients with moderate to severe renal impairment, though systemic absorption is minimal with appropriate topical use.

Contraindications

Hypersensitivity to mupirocin or any component of the formulation. Should not be used in patients with known hypersensitivity to polyethylene glycol, which is contained in the ointment base. Not recommended for use on burns exceeding 10% of body surface area due to potential for polyethylene glycol absorption and renal toxicity. Contraindicated for the treatment of fungal or viral skin infections without bacterial superinfection.

Possible side effects

Common side effects (affecting 1-10% of users) include application site reactions such as burning, stinging, or pain. Less frequently (0.1-1%), patients may experience itching, rash, dryness, nausea, or erythema. Rare side effects (<0.1%) include contact dermatitis, skin tenderness, and secondary infections. Systemic reactions are uncommon due to minimal absorption but may include headache and diarrhea in susceptible individuals.

Drug interaction

No clinically significant drug interactions have been reported with topical mupirocin ointment. However, concurrent use with other topical medications applied to the same area should be avoided unless directed by a physician, as the ointment base may affect absorption of other products. Systemic interactions are unlikely due to minimal absorption, but healthcare providers should be informed of all medications being taken, including over-the-counter products and supplements.

Missed dose

Apply the missed dose as soon as remembered, unless it is almost time for the next scheduled application. Do not double the dose to make up for a missed application. Maintain the regular dosing schedule, applying approximately every 8 hours. If multiple doses are missed, contact your healthcare provider for guidance on whether to extend the treatment duration.

Overdose

Topical overdose is unlikely to cause systemic effects due to limited absorption. However, excessive application may increase the risk of local adverse reactions including severe irritation, redness, or itching. If accidental ingestion occurs, seek medical attention immediately as polyethylene glycol components may cause gastrointestinal irritation. Symptomatic and supportive care should be provided as needed.

Storage

Store at room temperature between 15-30°C (59-86°F). Do not freeze. Keep the tube tightly closed when not in use. Protect from excessive heat and direct sunlight. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging. Discard any remaining medication after completion of treatment course.

Disclaimer

This information is for educational purposes only and does not replace professional medical advice. Always consult a qualified healthcare provider for diagnosis and treatment recommendations. Individual response to medication may vary, and proper diagnosis is essential before beginning treatment. The manufacturer and distributors are not liable for incorrect use or self-diagnosis.

Reviews

Clinical studies demonstrate Bactroban Ointment achieves clinical cure rates of 85-95% in impetigo patients when used as directed. Dermatologists frequently report excellent efficacy against Staphylococcal infections with minimal resistance development. Patients note rapid improvement in symptoms, typically within 2-3 days of initiation. The convenient tube size and application frequency are generally well-accepted by users. Some patients report mild application site reactions that typically resolve with continued use.