Lotrisone: Dual-Action Relief for Fungal Skin Infections
Lotrisone
| Product dosage: 10 gr | |||
|---|---|---|---|
| Package (num) | Per tube | Price | Buy |
| 5 | $8.20 | $41.00 (0%) | 🛒 Add to cart |
| 6 | $7.50 | $49.20 $45.00 (9%) | 🛒 Add to cart |
| 7 | $7.00 | $57.40 $49.00 (15%) | 🛒 Add to cart |
| 8 | $6.62 | $65.60 $53.00 (19%) | 🛒 Add to cart |
| 9 | $6.33 | $73.80 $57.00 (23%) | 🛒 Add to cart |
| 10 | $6.10
Best per tube | $82.00 $61.00 (26%) | 🛒 Add to cart |
| Product dosage: 20 gr | |||
|---|---|---|---|
| Package (num) | Per tube | Price | Buy |
| 2 | $21.00 | $42.00 (0%) | 🛒 Add to cart |
| 4 | $18.25 | $84.00 $73.00 (13%) | 🛒 Add to cart |
| 8 | $16.62 | $168.00 $133.00 (21%) | 🛒 Add to cart |
| 16 | $15.88
Best per tube | $336.00 $254.00 (24%) | 🛒 Add to cart |
Synonyms | |||
Lotrisone is a prescription-only topical medication combining two potent active ingredients—clotrimazole, a broad-spectrum antifungal agent, and betamethasone dipropionate, a high-potency corticosteroid. This synergistic formulation is specifically designed to treat inflammatory fungal infections of the skin, such as tinea corporis (ringworm), tinea cruris (jock itch), and tinea pedis (athlete’s foot), where significant redness, itching, and swelling are present. By addressing both the underlying fungal cause and the inflammatory response, Lotrisone offers comprehensive, rapid symptom relief and effective eradication of infection, making it a trusted choice among dermatologists for moderate to severe cases.
Features
- Contains 1% clotrimazole and 0.05% betamethasone dipropionate in a smooth, non-greasy cream base
- Available in 15g, 30g, and 45g tubes for convenient application
- Formulated for optimal cutaneous absorption without occlusion in most cases
- Combines antifungal and anti-inflammatory properties in a single preparation
- Clinically proven to reduce erythema, scaling, and pruritus within days
Benefits
- Rapid relief from itching, burning, and discomfort associated with fungal skin infections
- Dual mechanism targets both fungal pathogens and inflammatory mediators
- Reduces risk of secondary bacterial infections by minimizing scratching and skin breakdown
- Convenient twice-daily application regimen supports treatment adherence
- Helps prevent recurrence when used for full prescribed duration
- Minimizes post-inflammatory hyperpigmentation through controlled anti-inflammatory action
Common use
Lotrisone is primarily indicated for the treatment of tinea corporis (ringworm on the body), tinea cruris (jock itch), and tinea pedis (athlete’s foot) diagnosed by a healthcare provider. It is particularly appropriate for cases presenting with significant inflammation, erythema, and pruritus. The medication should be applied to affected areas twice daily, with treatment duration typically ranging from 1 to 4 weeks depending on infection severity and location. Diagnosis should be confirmed by potassium hydroxide (KOH) preparation or fungal culture before initiation, as corticosteroid components can mask symptoms or exacerbate certain conditions if misused.
Dosage and direction
Apply a thin layer of Lotrisone cream to cover the affected area and approximately 1 inch of surrounding healthy skin twice daily (morning and evening). Gently massage until absorbed. Wash hands thoroughly after application unless treating hands. Treatment duration should not exceed 2 weeks for tinea pedis or 4 weeks for other indications unless specifically directed by a physician. Do not use occlusive dressings unless advised by a healthcare provider, as this may increase systemic absorption of corticosteroids. If no clinical improvement is observed after the designated treatment period, reevaluation and confirmation of diagnosis is recommended.
Precautions
Use Lotrisone only as prescribed and for the condition for which it was prescribed. Avoid contact with eyes, mucous membranes, and open wounds. Do not use on the face, groin, or axillae unless directed by a physician. Prolonged use may lead to skin atrophy, striae, telangiectasias, and adrenal suppression. Pediatric patients may be more susceptible to systemic corticosteroid effects. Discontinue use if irritation develops and consult your physician. Patients should be advised that this medication is for external use only and should not be used for any disorder other than that for which it was prescribed.
Contraindications
Lotrisone is contraindicated in patients with known hypersensitivity to clotrimazole, betamethasone, other corticosteroids, or any component of the formulation. It should not be used for primary bacterial infections (impetigo, cellulitis), viral infections (herpes simplex, varicella), or tuberculous and fungal lesions of the skin not responsive to antifungal therapy. Contraindicated in patients with circulating fungal infections (candidemia). Should not be used in the treatment of acne rosacea, perioral dermatitis, or vulgaris.
Possible side effects
Most common side effects include burning, itching, irritation, and dryness at application site. Less frequently, may cause folliculitis, hypertrichosis, acneiform eruptions, and hypopigmentation. With prolonged use or over large surface areas: skin atrophy, striae, miliaria, telangiectasia. Systemic absorption may lead to reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with potential for glucocorticosteroid effects including hyperglycemia, glucosuria, Cushing’s syndrome, and delayed weight gain in pediatric patients. Allergic contact dermatitis may occur.
Drug interaction
No specific drug interactions with clotrimazole have been established. The corticosteroid component may interact with other topical products that increase systemic absorption. Concurrent use with other topical corticosteroids may increase systemic effects. Use with caution in patients receiving other drugs that suppress the immune system. Minimal interaction risk with systemic medications due to limited absorption, though patients on diabetes medications should be monitored for potential hyperglycemic effects.
Missed dose
Apply the missed dose as soon as remembered, unless it is almost time for the next scheduled application. Do not apply extra medication to make up for a missed dose. Maintain the regular twice-daily schedule without doubling applications. If multiple doses are missed or application irregularity persists, contact your healthcare provider for guidance on maintaining treatment efficacy.
Overdose
Topical overdose may produce systemic corticosteroid effects including hypertension, edema, hypokalemia, and adrenal suppression. Acute overdose is unlikely with topical application but could occur with application over large surface areas, prolonged use, or with occlusive dressings. Treatment should be symptomatic and supportive. If ingested orally, seek immediate medical attention as betamethasone may cause systemic effects. Gastric lavage or activated charcoal may be considered if ingestion occurred recently.
Storage
Store at controlled room temperature (20°-25°C or 68°-77°F). Do not freeze. Keep tube tightly closed when not in use. Protect from light and excessive heat. Keep out of reach of children and pets. Do not use after expiration date printed on packaging. Discard any medication that has changed color or consistency. Do not transfer to other containers.
Disclaimer
This information is provided for educational purposes only and does not constitute medical advice. Lotrisone is available by prescription only. Always consult with a qualified healthcare professional before starting, stopping, or changing any medication regimen. Individual results may vary. Proper diagnosis by a healthcare provider is essential before using this medication. Full prescribing information should be reviewed before use.
Reviews
Clinical studies demonstrate Lotrisone’s efficacy with 75-85% of patients achieving complete clearance of signs and symptoms within the treatment period. Dermatologists frequently report superior anti-inflammatory action compared to antifungal monotherapies in inflammatory tinea cases. Patients note significant pruritus relief within 3-5 days of initiation. Some studies indicate higher cure rates compared to clotrimazole alone for inflammatory fungal infections. Long-term safety data supports appropriate short-term use with minimal adverse events when used as directed.