Shuddha Guggulu: Natural Support for Healthy Cholesterol & Metabolism

Shuddha Guggulu
| Product dosage: 60caps | |||
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| 1 | $49.00 | $49.00 (0%) | 🛒 Add to cart |
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| 10 | $29.20
Best per bottle | $490.00 $292.00 (40%) | 🛒 Add to cart |
Shuddha Guggulu, derived from the purified resin of the Commiphora mukul tree, is a cornerstone of Ayurvedic medicine renowned for its lipid-modulating and anti-inflammatory properties. This traditional botanical supplement is extensively used to support cardiovascular wellness, promote healthy weight management, and maintain balanced metabolic function. Clinical and traditional evidence supports its role in holistic health regimens, particularly for individuals seeking natural adjuncts to lifestyle modifications. Proper usage under professional guidance ensures optimal benefits while minimizing risks.
Features
- Sourced from purified Commiphora mukul resin (guggul)
- Standardized to contain active guggulsterones (E and Z isomers)
- Prepared using classical Ayurvedic shodhana (purification) process
- Free from synthetic additives, binders, or artificial preservatives
- Laboratory tested for heavy metals, pesticides, and microbial contaminants
- Available in vegetarian capsule form for precise dosing
Benefits
- Supports healthy lipid metabolism by modulating cholesterol synthesis and clearance
- Promotes balanced inflammatory response through COX-2 inhibition and cytokine modulation
- Aids in weight management by enhancing thyroid function and thermogenesis
- Provides antioxidant protection against oxidative stress in vascular tissues
- Supports joint comfort and mobility through anti-arthritic mechanisms
- Maintains healthy skin through blood-purifying and anti-acne properties
Common use
Shuddha Guggulu is traditionally indicated for medoroga (disorders of fat metabolism), including hyperlipidemia and obesity. It is commonly used as complementary support for atherosclerosis management, metabolic syndrome, and osteoarthritis. Practitioners also prescribe it for skin conditions like acne and nodules, as well as for managing uterine disorders and benign growths. Modern applications include adjuvant therapy for thyroid disorders, particularly subclinical hypothyroidism, and as part of detoxification protocols in Panchakarma.
Dosage and direction
The typical adult dosage ranges from 500–1000 mg twice daily, taken with warm water. For cholesterol management: 750 mg thrice daily. For weight management: 500 mg before meals. For osteoarthritis: 1000 mg twice daily with ginger tea. Always begin with lower doses to assess tolerance. Take approximately 30 minutes before food for optimal absorption. Therapy duration typically spans 8–12 weeks, followed by a 2-week break before resuming if needed. Dosage adjustments should be made under Ayurvedic or medical supervision based on individual prakruti (constitution) and vikruti (imbalance).
Precautions
- Discontinue use if rash, gastrointestinal upset, or headache occurs
- Monitor liver enzymes periodically during extended use
- Not recommended during acute febrile illnesses or dehydration
- Use cautiously in patients with irritable bowel syndrome or hemorrhoids
- May require dosage adjustment in elderly patients or those with renal impairment
- Avoid concomitant use with other strong Pitta-aggravating substances
Contraindications
- Pregnancy and lactation (uterotonic effects)
- Acute hepatitis or liver cirrhosis
- Hyperthyroidism or uncontrolled thyroid disorders
- Known hypersensitivity to Commiphora species
- Active peptic ulcer disease or gastroesophageal reflux
- Surgical patients (discontinue 2 weeks preoperatively)
- Children under 18 years (unless specifically prescribed)
Possible side effects
- Mild gastrointestinal discomfort, nausea, or diarrhea (usually transient)
- Skin rash or urticaria in sensitive individuals
- Headache or dizziness (typically dose-dependent)
- Hepatic enzyme elevation with prolonged high-dose use
- Rare cases of thyroid stimulation leading to palpitations
- May aggravate Pitta dosha if used improperly
Drug interaction
- Potentiates effects of thyroid medications (monitor TSH levels)
- May reduce bioavailability of propranolol and diltiazem
- Enhances activity of statins (increased risk of myopathy)
- Interacts with tamoxifen metabolism via CYP2B6 inhibition
- May decrease efficacy of oral contraceptives
- Caution with anticoagulants due to mild antiplatelet activity
- Avoid with hepatotoxic drugs or strong CYP3A4 inducers
Missed dose
Take the missed dose as soon as remembered, unless it is nearly time for the next scheduled dose. Do not double the dose to catch up. Resume regular dosing schedule. Occasional missed doses are not critical due to cumulative effects, but consistent adherence maximizes therapeutic outcomes. Maintain a dosing diary if forgetfulness is frequent.
Overdose
Symptoms may include severe nausea, vomiting, abdominal pain, diarrhea, and skin eruptions. In extreme cases, thyroid storm manifestations or hepatotoxicity may occur. Management includes immediate discontinuation, gastric lavage if recent ingestion, and symptomatic treatment. Provide supportive care for dehydration and electrolyte imbalance. No specific antidote exists. Seek immediate medical attention for doses exceeding 5 grams.
Storage
Store in airtight containers away from light, moisture, and heat. Ideal temperature: 15–30°C. Keep original container tightly sealed after each use. Do not refrigerate. Discard if capsules become discolored, develop unusual odor, or after expiration date. Keep out of reach of children and pets. Shelf life: 24 months from manufacturing date when stored properly.
Disclaimer
This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Consult your healthcare provider before use, especially if you have medical conditions or take prescription medications. Ayurvedic supplements should be used under qualified practitioner guidance. Individual results may vary based on constitution, lifestyle, and adherence to dietary guidelines.
Reviews
“After 3 months of Shuddha Guggulu, my lipid profile improved significantly without statin side effects. My Ayurvedic doctor monitored my progress closely.” — Priya M., 52
“Effective for my PCOS-related weight issues. Combined with diet changes, I lost 8 kg in 12 weeks. Mild initial nausea subsided after first week.” — Anjali R., 34
“Remarkable improvement in knee osteoarthritis pain. I take 1000 mg twice daily with Ashwagandha. Reduced my NSAID use by 70%.” — Rajesh K., 61
“Noticed better skin texture and reduced acne outbreaks within 6 weeks. No digestive issues when taken with warm water.” — Sneha P., 28
“My borderline hypothyroidism improved with Shuddha Guggulu and lifestyle modifications. TSH normalized after 4 months of consistent use.” — Vikram S., 45