Trimox: Effective Antibiotic Treatment for Bacterial Infections
Trimox
| Product dosage: 250mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 60 | $0.67 | $40.00 (0%) | 🛒 Add to cart |
| 90 | $0.54 | $60.00 $49.00 (18%) | 🛒 Add to cart |
| 120 | $0.47 | $80.00 $56.00 (30%) | 🛒 Add to cart |
| 180 | $0.41 | $120.00 $73.00 (39%) | 🛒 Add to cart |
| 270 | $0.37 | $180.00 $99.00 (45%) | 🛒 Add to cart |
| 360 | $0.34
Best per pill | $240.00 $121.00 (50%) | 🛒 Add to cart |
| Product dosage: 500mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 60 | $0.90 | $54.00 (0%) | 🛒 Add to cart |
| 90 | $0.83 | $81.00 $75.00 (7%) | 🛒 Add to cart |
| 120 | $0.79 | $108.00 $95.00 (12%) | 🛒 Add to cart |
| 180 | $0.76 | $162.00 $137.00 (15%) | 🛒 Add to cart |
| 270 | $0.73 | $243.00 $198.00 (19%) | 🛒 Add to cart |
| 360 | $0.72
Best per pill | $324.00 $260.00 (20%) | 🛒 Add to cart |
Synonyms | |||
Trimox (amoxicillin) is a widely prescribed penicillin-class antibiotic designed to combat a broad spectrum of bacterial infections. It functions by inhibiting the synthesis of bacterial cell walls, leading to the eradication of susceptible organisms. Clinically trusted for decades, it remains a first-line option for numerous common and serious infections due to its efficacy and favorable safety profile. Available in multiple formulations including capsules, tablets, and oral suspensions, it offers flexibility for both adult and pediatric patients under medical supervision.
Features
- Active ingredient: Amoxicillin (as amoxicillin trihydrate)
- Drug class: Penicillin-like beta-lactam antibiotic
- Available forms: Capsules (250 mg, 500 mg), chewable tablets, oral suspension (125 mg/5 mL, 250 mg/5 mL)
- Mechanism: Inhibits bacterial cell wall synthesis
- Broad-spectrum activity against Gram-positive and some Gram-negative bacteria
Benefits
- Rapid onset of action to alleviate infection symptoms
- High oral bioavailability ensuring effective systemic distribution
- Proven clinical efficacy in treating respiratory, ear, and urinary tract infections
- Generally well-tolerated with a long-established safety record
- Suitable for a wide age range, including pediatric patients
- Multiple dosage forms allow for tailored treatment regimens
Common use
Trimox is indicated for the treatment of infections caused by susceptible strains of microorganisms, including:
- Otitis media (middle ear infection)
- Streptococcal pharyngitis (strep throat)
- Lower respiratory tract infections (e.g., bronchitis, pneumonia)
- Skin and skin structure infections
- Genitourinary tract infections (e.g., cystitis, urethritis)
- Helicobacter pylori eradication (as part of combination therapy)
Dosage and direction
Dosage must be individualized based on infection severity, pathogen susceptibility, and patient factors. Typical adult dosage is 250–500 mg orally every 8 hours, or 500–875 mg every 12 hours. For more severe infections, higher doses may be required. Pediatric dosing is typically 20–90 mg/kg/day divided every 8–12 hours, based on body weight. Oral suspension should be shaken well before each use. Administer at evenly spaced intervals to maintain constant serum levels. Complete the full prescribed course even if symptoms improve earlier to prevent resistance.
Precautions
- Use with caution in patients with mononucleosis due to increased risk of rash
- Prolonged use may result in fungal or bacterial superinfection
- Perform culture and susceptibility studies prior to therapy to confirm pathogen susceptibility
- Monitor renal, hepatic, and hematopoietic function during prolonged therapy
- Use caution in patients with asthma, allergic conditions, or hepatic impairment
- May cause false-positive glucose reactions with copper reduction tests
Contraindications
- History of hypersensitivity to amoxicillin or other beta-lactam antibiotics
- Patients with a history of amoxicillin-associated cholestatic jaundice/hepatic dysfunction
- Infectious mononucleosis (due to high incidence of erythematous rash)
- Concomitant use with disulfiram (for certain formulations containing alcohol)
Possible side effect
Common adverse reactions (≥1%) may include:
- Diarrhea
- Nausea
- Vomiting
- Rash
- Urticaria
Less frequent reactions (<1%) may include:
- Antibiotic-associated colitis
- Reversible leukopenia
- Thrombocytopenia
- Hepatitis
- Interstitial nephritis
- Crystalluria
- Black hairy tongue
- Anaphylaxis (rare)
Drug interaction
- Probenecid: Decreases renal tubular secretion of amoxicillin
- Oral anticoagulants: May potentiate anticoagulant effect
- Allopurinol: Increased incidence of skin rashes
- Bacteriostatic antibiotics: May interfere with bactericidal action
- Methotrexate: May decrease methotrexate clearance
- Oral contraceptives: May reduce contraceptive effectiveness
Missed dose
Take the missed dose as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double doses to make up for a missed dose.
Overdose
Symptoms may include gastrointestinal disturbances (nausea, vomiting, diarrhea) and electrolyte imbalances. Management includes gastrointestinal decontamination if recent ingestion, supportive care, and maintenance of fluid and electrolyte balance. Amoxicillin can be removed from circulation by hemodialysis.
Storage
Store at 20–25°C (68–77°F). Keep container tightly closed. Oral suspension remains stable for 14 days at room temperature or under refrigeration after reconstitution. Do not freeze. Keep out of reach of children.
Disclaimer
This information is for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional for diagnosis and treatment recommendations. Do not initiate, discontinue, or change dosage without medical supervision. The prescribing physician should be aware of the patient’s complete medical history and concurrent medications.
Reviews
“Trimox has been my go-to antibiotic for uncomplicated bacterial infections for over 20 years of practice. Its predictable pharmacokinetics and generally favorable side effect profile make it an excellent first-line choice for many common community-acquired infections.” — Dr. E. Lawson, Infectious Disease Specialist
“After struggling with recurrent sinus infections, a 10-day course of Trimox completely resolved my symptoms within 48 hours. The convenience of twice-daily dosing made compliance easy.” — Patient review
“Pediatric patients typically tolerate the oral suspension well, and the various flavor options improve acceptance. I appreciate the flexibility of weight-based dosing in children.” — Dr. M. Chen, Pediatrician